Id like to see locations not as where you are, but where you could go. Say auction house, spend 7 and search your deck for any equipment item, place it in your hand. Stormwind: spend 7 to recieve "blessing of the dragonslayer" all allies and heroes recieve +3Att and HP this turn...
Expensive to use since travel is costly because of how much time it takes to get anywhere (yay teleport!), but the effect could be great.
Also they could tie it in with professions, like Un'Goro Crater (requires Skinning, Herbalism, and/or Mining): Skinners recieve +1 resource this turn, Herbalist recieve +2 resources this turn, Miners recieve +2 resources this turn...that would give some balance because I know some heroes are double gathering, and I cant see how else they will recieve benefits when professions are introduced (the devs have talked about what professions will get, crafters will have access to more equipment).
Locations may aslo include some sort of byline like "remove location from game if hero enters combat on his turn" meaning, the hero went there, got what he wanted, and then left.